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About Mini IVF Procedure and Micro IVF Success Rates

| 15 Jun 2020 | 2610 Views |

IVF today has become a common term. It is a very popular term among couples deprived of the happiness of a child. It is also recognized by the term In-vitro Fertilization. The frequently used mini IVF procedure is the treatment recommended by IVF specialists for couples suffering from infertility problems. The success rate is higher and depends on certain factors that need to be followed strictly.

Mild IVF (or mini IVF or micro IVF) or Gentle IVF or IVF Lite

Mini IVF process is performed exactly as a conventional IVF procedure is performed. In this process, the hormones which are utilized to stimulate the ovaries to produce a good quantity of eggs are given at a low dose or for a shorter period. This could be used to decrease the risk of ovarian hyperstimulation syndrome in women who developed OHSS in the last IVF cycles and women who have developed polycystic ovary syndrome (PCOS).

Mild stimulation might lead to omitting the initial treatment and suppressing women’s menstrual cycle. One may not find the initial phase of the treatment uncomfortable.

Know More About Mini IVF Procedure

Here is a complete guide on the mini IVF procedure. This procedure may vary from clinic to clinic but the common method followed is:

  • Before beginning with mini IVF treatment, women are advised to take at least one course of birth control pills to normalize their cycle.
  • The doctor would go for an ultrasound to make sure that you are good for IVF.
  • After the check-up, if everything is good, the doctor will recommend medications to stimulate ovulation, resulting in the production of more eggs than usual.
  • When the follicles are ripe and mature, the doctor will give a human chorionic gonadotropin injection.
  • IVF will conventionally take place. The egg will be retrieved, fertilization will take place and the embryo will be transferred to the womb.

If a woman selects mini IVF, she may still need some fertility medicines. Doses are less. In this, women can avoid the daily dose of injections. Avoiding injections also reduce the chances of the ovarian hyper-stimulation syndrome (OHSS). It is a complication expected with standard IVF treatment. It is your treating doctor who is the right person to decide if you need to go for a mini IVF procedure or prefer some other option.

For whom is the Mini-IVF suitable?

Mini-IVF may be a good option for some but not favorable for others. It should be considered by the females experiencing the below situations:

  • One who has PCOS and is at the risk of OHSS development.
  • Ladies fear the intake of needles. In this process, less amount of fertility
  • drugs is used resulting in the minimum use of injections.
  • If you have reserves of low ovarian.
  • If you are to commence treatment for any type of cancer diagnosed earlier.

How is the Mini IVF Treatment Performed?

Mini IVF treatment might be bound to result in pregnancy than regular cycle IVF, which utilizes no fertility prescriptions. However, Mini IVF success rates are lower than standard IVF success rates.

During the Mini IVF treatment, Clomid /letrozole might be utilized to stimulate the ovaries instead of using gonadotropins. Sometimes, low doses of gonadotropins might be utilized with the main objective of producing a couple of eggs.

In many cases, it is possible to perform mini-IVF without using ovulation stimulation medications. This is called a natural cycle.

A natural mini IVF cycle is not suitable if there are any complications with ovulation that prevents pregnancy. This will be an acceptable choice for women facing the problem of blocked fallopian tubes.

Apart from the ovarian stimulation medicines, you might need to take a GnRH antagonist which helps in preventing ovulation from happening very early. If women ovulate very early then the eggs cannot be retrieved and IVF won’t take place.

Mini IVF Egg Retrieval

Mini IVF egg retrieval is the process of taking eggs from women’s bodies after maturation. People who promote mini IVF protocols claim that giving low doses of drugs leads to fewer but good-quality eggs.

For instance, in the investigation of mini IVF referenced above, birth rates were 22% lower for patients treated with mini IVF protocols. If it were genuine that low-portion IVF brings about more excellent eggs, we would hope to see comparative birth rates for cycles utilizing minimal stimulation.

Mini IVF is defined as the cycle that utilizes fewer doses of the injections utilized in standard IVF. It utilizes less powerful medications like Clomid. Low doses of drugs lead to 1-4 eggs retrieved upon maturation. Mini IVF egg retrieval is very important and is performed under the expert observation of an experienced IVF doctor only.

“The cases of infertility in not only males but also in the females are constantly increasing. It is majorly because of the unhealthy modern lifestyle. It is a serious issue and needs due attention. I have successfully treated many infertile patients and hope youths will understand the importance of good habits and healthy living,” says Dr. Richika Sahay Shukla, Director, India IVF Infertility Clinic.

The difficulties of this type of In Vitro Fertilization are diminished quantities of eggs accessible for collection, thus conceivably fewer embryos to browse for transfer. Moreover, ovaries are also not stimulated similarly. Women do not have to wait for a long time to repeat a cycle of IVF. One can have three to four cycles in a period of six months.

The comparable outcomes, together with the huge contrast in cost, imply this is turning into an infertility treatment deserving of more thought.

The Mini IVF India

There are many clinics dedicated to mini IVF India treating needy patients/couples. These clinics have the required experience. The success rate of the treatment is the trademarked minimal stimulation in IVF protocols. These clinics offer a holistic approach towards fertility care and offer an excellent alternative to standard IVF.

Only 3-5 eggs are needed for a healthy baby. When high doses of drugs are given then more than 5 eggs are produced which are not viable. Sometimes, extra eggs are discarded before embryo transfer or are at risk of a natural miscarriage.

Micro IVF Success Rates

Micro IVF success rates are comparatively lower than standard IVF but this does not state that it is not a good choice for some couples.A random study made a comparison between standard IVF treatment and mini IVF treatment.

The study stated that 570 women of age 39 years or younger were selected. Some went for mini IVF and some went for standard IVF. They underwent the treatment for around six months.

The results were as follows:
  • 50% of the patients who underwent mini IVF treatment conceived and gave birth to a healthy baby.
  • 63% of the patients who underwent standard IVF treatment conceived and gave birth to a healthy baby.
  • Women who underwent mini IVF treatment did not develop ovarian hyperstimulation syndrome.
  • 8% of women who underwent mini IVF treatment developed ovarian hyperstimulation syndrome.
  • Moreover, low doses of gonadotropins were utilized in the mini IVF treatment and it lowered the cost of treatment.

Based on the above results, mini IVF treatment may be an excellent choice for women at risk of developing ovarian hyperstimulation syndrome. A study found that the rate of giving birth to twins is much less in mini IVF.

If we compare standard IVF treatment to mini IVF treatment, it is observed that mini IVF costs less per cycle. It also reduces the risk of developing ovarian hyperstimulation syndrome. But the success rates are a bit low. As compared to IUI, mini IVF costs a bit more than IUI but it has improved success rates. There are fewer chances of conceiving multiples in mini IVF as compared to conventional treatment.

Although the mini IVF procedure is common today, it is necessary to undergo any kind of treatment related to infertility problems under the expert guidance of an IVF specialist only.

About The Author
Dr. Richika Sahay

MBBS (Gold Medalist), DNB (Obst & Gyne), MNAMS, MRCOG (London-UK), Fellow IVF, Fellow MAS, Infertility (IVF) Specialist & Gynae Laparoscopic surgeon,[Ex AIIMS & Sir Gangaram Hospital, New Delhi]. Read more

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