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How Does Ovarian PRP Work

How Does Ovarian PRP Work? Delving Deep into Fertility Enhancements

| 25 Oct 2023 | 47707 Views |


Ovarian PRP, or Ovarian Platelet-Rich Plasma, is a technique used at India IVF Fertility to improve egg quality in fertility treatments. This innovative procedure involves injecting a concentrated solution of platelets into the ovaries, which contain growth factors that stimulate the production of new cells and improve tissue regeneration. By enhancing the development of healthy eggs, Ovarian PRP can significantly impact the success rates of fertility treatments. This blog post aims to provide a comprehensive understanding of Ovarian PRP and its effectiveness in improving egg quality. It is an informative resource for individuals seeking fertility treatments and couples struggling with infertility.

How Does Ovarian PRP Work?

Ovarian PRP, short for Ovarian Platelet-Rich Plasma, is a cutting-edge technique used to enhance egg quality in fertility treatments. This procedure involves injecting a concentrated solution of platelets directly into the ovaries. Platelets are small blood cells that play a crucial role in clotting and wound healing. They contain growth factors, such as platelet-derived growth factor (PDGF) and transforming growth factor-beta (TGF-β), which are essential for tissue regeneration and repair.

During the Ovarian PRP procedure, a small amount of blood is drawn from the patient. The blood is then processed using a centrifuge machine to separate the platelets from other components, such as red blood cells and plasma. Once the platelets are isolated, they are injected into the ovaries.
Once inside the ovaries, the platelets release their growth factors. These growth factors stimulate cell division and proliferation, promoting the development of healthy eggs. They also improve overall egg quality by enhancing mitochondrial function and reducing oxidative stress within the ovarian environment.

By introducing concentrated platelets with their growth factors directly into the ovaries, Ovarian PRP harnesses the regenerative potential of these cells to optimize egg quality. This innovative technique offers hope to individuals struggling with infertility by providing a natural way to improve their chances of successful conception and pregnancy.

Does Ovarian PRP Work?

The medical community is still conducting extensive research on this but the results so far are promising. Ovarian PRP injections have been shown to improve ovarian reserve parameters and IVF outcomes in women with POR.

Study Population Intervention Outcomes
Cakiroglu et al. (2021) Women with poor ovarian response (POR) Intraovarian injection of PRP Increased antral follicle count (AFC) and AMH levels, but not FSH levels. 64.8% of PRP-treated women developed antral follicles.
Sills et al. (2021) Women with POR who had previously failed IVF due to genetically abnormal embryos Intraovarian injection of PRP Healthy 46, XY pregnancy with IVF after intraovarian injection of PRP.
Evaluation of intra-ovarian platelet-rich plasma administration on oocytes-dependent variables in patients with poor ovarian response: A retrospective study according to the POSEIDON criteria (2022) Women with POR Intraovarian injection of PRP Increased number of oocytes, fertilization rates, and blastocysts per cycle.
Study of PRP in Women With Evidence of Diminished Ovarian Reserve (NCT04275700) Women with a history of poor response to ovulation induction Intraovarian injection of PRP Ongoing study, results not yet published.
Ovarian PRP (Platelet Rich Plasma) Injection for Follicular Activation (OPIF) (NCT05279560) Women with diminished ovarian reserve Intraovarian injection of PRP Ongoing study, results not yet published.

How Does Ovarian PRP Improve Egg Quality?

Ovarian PRP has shown significant effectiveness in improving egg quality, thereby increasing the chances of successful fertility treatments. Studies have demonstrated that this innovative technique can have a positive impact on the quality of eggs produced by the ovaries.

The growth factors released by the platelets during Ovarian PRP stimulate the ovaries to produce healthier eggs. These growth factors promote cell division and proliferation within the ovarian follicles, leading to the development of high-quality eggs. By enhancing mitochondrial function and reducing oxidative stress, Ovarian PRP creates a more favorable environment for egg maturation.
Improved egg quality is crucial for successful fertilization and pregnancy. High-quality eggs have a higher chance of being successfully fertilized by sperm and developing into healthy embryos. This can significantly increase the likelihood of achieving a successful pregnancy.

For individuals undergoing fertility treatments, such as in vitro fertilization (IVF) or intrauterine insemination (IUI), incorporating Ovarian PRP can be a valuable addition to enhance their chances of success. By improving egg quality, Ovarian PRP offers new hope for individuals struggling with infertility, providing them with an opportunity to fulfill their dreams of starting or expanding their family.

The Potential of Ovarian PRP in Improving Egg Quality

Ovarian PRP holds great promise as a technique for improving egg quality in fertility treatments. By stimulating the production of healthy eggs, it has the potential to significantly increase the chances of successful pregnancy. For individuals seeking fertility treatments, considering Ovarian PRP as part of their treatment plan could be a beneficial option. It is important to have a discussion with healthcare providers who specialize in fertility and reproductive medicine to explore the potential benefits and determine if Ovarian PRP is suitable for individual circumstances. With ongoing advancements in reproductive technology, Ovarian PRP offers new hope and possibilities for individuals struggling with infertility on their journey towards parenthood.


Ovarian PRP therapy offers a glimmer of hope to many who are seeking to improve their fertility outcomes. While it’s not a guaranteed solution, it provides another avenue to explore in the intricate journey of conception. Always consult with a trusted fertility specialist, like those at *India IVF Fertility*, to understand the best options available.


Ovarian PRP refers to the use of Platelet-rich plasma in the ovaries to potentially improve fertility outcomes.

PRP is derived from the patient's own blood, which is then processed to increase the concentration of platelets.

No treatment can guarantee a successful pregnancy, but PRP offers a new avenue to explore for those seeking fertility enhancements.

As with any procedure, there can be side effects. It's crucial to discuss these with a fertility specialist.

The frequency of treatment varies based on individual needs and the recommendation of the fertility specialist.

Some discomfort can be expected, but clinics take measures to ensure patient comfort during the procedure.

Typically, a session can take about 30 minutes to an hour.

Age can be a factor in fertility treatments. It's best to discuss this with a specialist.

Yes, many clinics combine PRP with other fertility enhancement methods.

Results can vary. It's essential to maintain regular follow-ups with the fertility clinic to monitor progress.

About The Author
Dr. Richika Sahay

MBBS (Gold Medalist), DNB (Obst & Gyne), MNAMS, MRCOG (London-UK), Fellow IVF, Fellow MAS, Infertility (IVF) Specialist & Gynae Laparoscopic surgeon,[Ex AIIMS & Sir Gangaram Hospital, New Delhi]. Read more

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