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Noninvasive Prenatal Testing (NIPT)

What is noninvasive prenatal testing (NIPT)

Noninvasive prenatal testing (NIPT Test) often known as noninvasive prenatal screening (NIPS Test), is a process of characterizing the threat that a fetus will be born with a definite hereditary deformity. This inspection observes tiny parts of DNA that are wandering in a pregnant lady’s blood.


Contrary to most DNA that is found in the cell’s nucleus, these particles are free circulating and but not inside the cell, so they are termed called cell-free DNA (cfDNA). These tiny particles normally hold less than 200 DNA building blocks (base pairs) and occur when cells are broken down or die off. Thus their ingredients, including DNA, are circulated inside the bloodstream.

NIPT Test checks for Patau syndrome (trisomy 13), Edwards syndrome (trisomy 18) Down syndrome, and (trisomy 21). And they can result in minor to major intelligence incapability and are related to deep, inborn deformity.

NIPT Test is more precise than a conventional first-trimester test, and there is a low chance of wrong positive and negative results. That eventually means that it will be a low chance your surgeon would suggest follow-up screening like amniocentesis.

DiGeorge syndrome (22q11.2 deletion) is another testing method if chosen. This syndrome can result in low calcium levels in the blood, a crevice appetite, weak immunity, heart deficiency, etc. The features of this syndrome can vary from person to person, even between individuals with similar chromosome removal.

Sex Chromosome oddities such as Klinefelter syndrome (47, XXY) and Turner syndrome (45,X) can also be identified, but the accuracy is disputed. Sex Chromosome oddities are commonly medically slighter than other chromosomal oddities.

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Who should get the NIPT Prenatal Test & NIPT Test Cost

  • NIPT is generally recommended to women based on their OB-GYN advice and procedure. However, there are some risk factors that compel your surgeon to recommend it strongly
  • Paternal and maternal chromosomal abnormality
  • Family or individual history of a pregnancy with a chromosomal abnormality
  • The age of women is 35 and older during the delivery

The decision to take NIPT Test screening is an individual’s personal decision, so you can take time and have a second opinion. It is up to you, what would be best for you. If you don’t know what to do, then you can have a word with our renowned surgeon and genetic counselor. He will help you by giving you the best advice as per your case scenario.

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