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What is a trigger shot IUI

What is a trigger shot IUI?

| 21 Nov 2023 | 20384 Views |

A glimmer of hope is provided by assisted reproductive technologies such as intrauterine insemination (IUI) for many couples facing the difficult path of infertility.

Of all the elements of an IUI procedure, the “trigger shot” is one of the most important since it affects the likelihood of a successful pregnancy. Let’s examine the specifics of what an IUI trigger shot comprises and how it advances the procedure as a whole.

What Is Human Chorionic Gonadotropin Hormone (hCG)?

For the body to produce enough progesterone to maintain pregnancy throughout the first trimester, hCG is an essential hormone in the early stages of pregnancy.

Preparing For An hCG Shot

Parents in waiting undergo physical exams and other testing to ensure their bodies are in good shape and prepared for the surgery. A gynecologist will perform a transvaginal ultrasound and hormone blood tests before administering an hCG trigger injection.

The hCG injection will be given once the gynecologist measures the ovarian follicles to the appropriate diameter. It takes 36 to 42 hours for eggs to become ripe for fertilization after injection.

The mother will have an ultrasound, blood tests, ovarian function testing, and health examinations of her reproductive organs. To examine sperm count, concentration, form, and motility, the father will have a medical examination and analyze his semen.

Why Do I Need an hCG Trigger Shot?

The goal of the hCG trigger injection is to start the ovulation cycle at the best possible time for a baby. It is frequently recommended for women who have irregular periods, aberrant hormone levels, or infertility that doesn’t make sense.

Seven days following the prime conception time, a progesterone test is conducted to confirm the increase in progesterone levels. Supplemental progesterone supplements may be provided as supplementary therapy if low levels continue.

How Does An IUI Procedure Work?

The artificial insemination technique known as intrauterine insemination (IUI) is used to treat infertility in couples. Sperm must be cleaned and concentrated upon before fertilizing eggs in the womb.

The operation has no unpleasant side effects and takes less than two minutes. To make sure there are healthy, highly concentrated sperm, the semen sample is treated and cleaned. IUI occurs when the eggs are at their best for fertilization and is finished in two days.

How Fertilization Occurs

Although human sperm may live in a woman’s reproductive system for up to five days, an excess of reactive oxygen species (ROS) can cause physical stress and oxidative damage.

As a result, sperm cells cannot initiate an efficient antioxidant response that would otherwise activate genes that defend against oxidative damage.

Additionally, the woman’s immune system forges a natural barrier against infection. Merely a few thousand sperm out of millions normally make it to the woman’s fallopian tubes, where one or more can reach and fertilize an egg or egg.

After Fertilization

A pregnancy test is conducted fourteen days after the optimal period for conception and fertilization. A positive test means that a new life has been successfully created; on the other hand, a negative test means that the procedure has to be restarted or that other fertility options need to be investigated.

Read Also- IVF vs IUI: A Comprehensive Comparison for Aspiring Parents

Are There Any Side Effects Of The hCG Trigger Shot?

The hCG trigger injection is safe and successful, according to clinical research. Still, there are some major health hazards associated with it, including ovarian cysts, ovarian hyperstimulation syndrome (OHSS), blood clots, and ovarian soreness.

Soreness and/or bruising near the injection site are common side effects, as is lower abdomen soreness or pain resulting from slightly enlarged ovaries. Breast soreness, gas, bloating in the abdomen, nausea, sore throat, upper respiratory tract infection, and itching are some infrequent adverse effects.

Before getting the injection, speaking with a gynecologist about potential side effects is crucial to ensure mom and baby have the best possible result.

How Much Is An IUI Trigger Shot?

With an IVF specialist administering medications such as gonadotropins, the main goal of IUI therapy is to encourage ovaries to generate one healthy egg, which can result in an overall cost rise of up to Rs. 40,000.

Is hCG Injection Necessary For IUI?

Human Chorionic Gonadotropin Hormone (hCG), or “trigger” injections, are a treatment option for infertility in women. The eventual baby’s health won’t suffer due to this approach.

How Successful Is A Trigger Shot?

Pregnancy rates following in vitro fertilization (IVF) have been reported to rise from 5.8% to 18.2% using trigger injections and even higher when timed to coincide with the woman’s natural spike in LH.

Another study highlighted the significance of trigger shots in IVF cycles by finding a greater pregnancy rate (19.6%) in cycles administered after IUI compared to 24 to 32 hours before the procedure (10.9%).


Within the field of infertility therapies, an IUI trigger shot is a calculated intervention used to maximize the likelihood of pregnancy. Comprehending its function, the associated procedures, and the elements impacting achievement may enable partners to pursue parenting.

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