Does Pentoxifylline have side effects on the embryo?

No. Pentoxifylline is used only at the sperm-selection stage in the lab and for a very short duration. The medium is washed off before ICSI, and it does not affect embryo development.

How much does it increase success rates?

Pentoxifylline can improve fertilisation rates in cases of poor or immotile sperm by helping identify viable sperm. However, outcomes vary and depend on multiple factors such as egg quality, embryo development, and overall reproductive health.

Is this procedure painful?

No. Pentoxifylline is a laboratory-based process applied to the sperm sample. There is no additional procedure or pain for the patient beyond routine semen collection or TESE, if required.

Reactivating Hope with Sperm Pentox

Pentoxifylline (Sperm Pentox) is a specialised laboratory agent used to improve sperm motility and viability in cases of male infertility with poor or immotile sperm. By enhancing cellular activity and oxygen utilisation, it helps embryologists identify viable sperm for procedures like ICSI, especially in samples where sperm movement is minimal or absent.

Enhancing Viability for IVF Success

What is Sperm Pentox?

Pentoxifylline, commonly referred to as Sperm Pentox, is a medication originally used to improve blood circulation by enhancing oxygen delivery to tissues. In reproductive medicine, it plays an important role in managing oligoasthenozoospermia—a condition marked by low sperm count and poor motility.

When added to a sperm sample in the laboratory, Pentoxifylline acts as a cellular stimulant that helps improve sperm function and selection during assisted reproduction.

Boosts Motility: Stimulates sluggish or lethargic sperm, encouraging movement and tail activity.
Identifies Viable Sperm: Helps differentiate between living but immotile sperm and non-viable sperm.
Improves Fertilisation Potential: Supports better sperm selection during ICSI, increasing the likelihood of successful fertilisation.

Who is Sperm Pentox For?

This therapy is designed for men experiencing challenges with sperm movement and quality.

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Asthenozoospermia

Men with reduced sperm motility, where sperm move slowly or inefficiently. Pentoxifylline helps stimulate sperm activity, improving speed and forward progression.

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Immotile Sperm

Cases where 100% of sperm appear motionless under the microscope. Sperm Pentox helps differentiate living but dormant sperm from non-viable sperm, enabling accurate selection.

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TESE / Surgical Retrieval

Sperm obtained directly from the testes through TESE or surgical retrieval are often immature and immotile. Pentoxifylline assists embryologists in identifying the most viable sperm for IVF/ICSI.

The Sperm Pentox Therapy

How we improve fertilisation rates in the lab.

Sample Collection

Semen is collected either through ejaculation or surgical retrieval (TESE), depending on the clinical requirement.

Pentox Application

The sperm sample is carefully washed and treated with Pentoxifylline (Sperm Pentox) under controlled laboratory conditions.

Activation

Within minutes, viable sperm show tail movement or twitching, helping embryologists identify living sperm cells.

Selection & ICSI

Only activated, viable sperm are selected and injected into the egg during ICSI to optimise fertilisation.

Frequently Asked Questions

Expert Care for Male Infertility

Low sperm motility doesn’t have to limit your chances of parenthood. At India IVF, advanced techniques like Sperm Pentox help address even complex male-factor infertility cases with precision and care.