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Low AMH Levels

Low AMH Levels: Causes, Symptoms, and Treatment Options for Better Fertility

| 01 Jun 2024 | 18624 Views |

1. What is AMH?

Understanding AMH and Its Role in Fertility

  • Anti-Müllerian Hormone (AMH): A hormone produced by ovarian follicles.
  • Role in Fertility: Indicates ovarian reserve (the number of eggs remaining).

AMH Levels by Age:

  • 20-24 years: 3.0-5.0 ng/mL
  • 25-29 years: 2.5-4.5 ng/mL
  • 30-34 years: 2.0-4.0 ng/mL
  • 35-39 years: 1.5-3.5 ng/mL
  • 40-44 years: 0.5-2.5 ng/mL
  • 45+ years: 0.1-1.0 ng/mL

2. Top 5 Causes of Low AMH Levels

1. Age (35%): The primary factor affecting AMH levels. AMH declines naturally with age, particularly after age 35.
2. Lifestyle Factors (20%): Poor diet, lack of exercise, smoking, and alcohol consumption can lower AMH levels.
3. Polycystic Ovary Syndrome (PCOS) (15%): A common hormonal disorder affecting ovarian function and AMH production.
4. Endometriosis (10%): Causes ovarian damage, leading to reduced AMH levels.
5. Medical Treatments (10%): Chemotherapy and previous ovarian surgeries can significantly reduce AMH levels.

3. Top 5 Signs and Symptoms of Low AMH Levels

1. Irregular Menstrual Cycles (30%): One of the most common symptoms, indicating hormonal imbalance.
2. Shorter Menstrual Cycles (25%): A sign of diminished ovarian reserve.
3. Premature Ovarian Aging (20%): Symptoms similar to early menopause, including hot flashes and night sweats.
4. Difficulty Conceiving (15%): Reduced fertility and longer time to achieve pregnancy.
5. Low Antral Follicle Count (10%): Fewer follicles visible during an ultrasound, indicating lower egg reserve.

4. Diagnosing Low AMH Levels

  • Fertility Tests and AMH Levels
  • Blood Test: Primary method for measuring AMH.

Complementary Tests:

  • Follicle Stimulating Hormone (FSH)
  • Antral Follicle Count (AFC)

5. Impact of Low AMH on Fertility

How Low AMH Affects Pregnancy Chances

  • Reduced Egg Reserve: Fewer eggs available for fertilization.
  • Fertility Treatment Necessity: Assisted reproductive technologies often required.

6. Treatment Options for Low AMH Levels

Medical Interventions for Low AMH

  • Fertility Medications: Stimulate egg production.
  • IVF (In Vitro Fertilization): Common approach for women with low AMH.

7. Natural Ways to Improve AMH Levels

Lifestyle Changes to Boost AMH

  • Healthy Diet: Rich in vitamins and antioxidants.
  • Regular Exercise: Promotes overall reproductive health.

Yoga, Acupuncture, and Supplements

  • Alternative Therapies: Yoga and acupuncture can support fertility.
  • Supplements: DHEA, Vitamin D, and L-arginine.

8. IVF Treatment for Low AMH Levels

How IVF Works with Low AMH

  • Ovarian Stimulation: Medication to produce multiple eggs.
  • Egg Retrieval and Fertilization: Eggs are fertilized in the lab.

Success Rates of IVF with Low AMH

Factors Influencing Success: Age, egg quality, and uterine health.

9. Donor Eggs and IVF

Using Donor Eggs in IVF

  • When to Consider: Extremely low AMH or poor-quality eggs.
  • Success Rates: Higher success rates with donor eggs.

10. Frequently Asked Questions

Can I conceive with low AMH?

Answer: Yes, though assisted reproductive technologies may be needed.

What happens if AMH is low?

Answer: Indicates reduced ovarian reserve and may suggest early menopause.

How to increase low AMH levels?

Answer: Healthy lifestyle, diet, exercise, and supplements can help.

References

Zaghloul, Y.I., Amin, Y.M., Mansour, R.T. (2020). Middle East Fertility Society Journal.

Steiner AZ, Pritchard D, Stanczyk FZ. (2017). Journal of the American Medical Association (JAMA).

Tables and Data

AMH Levels by Age Group:

Age Group AMH Range (ng/mL)
20-24 years 3.0 – 5.0
25-29 years 2.5 – 4.5
30-34 years 2.0 – 4.0
35-39 years 1.5 – 3.5
40-44 years 0.5 – 2.5
45+ years 0.1 – 1.0

Top Causes of Low AMH Levels:

Cause Percentage
Age 35%
Lifestyle Factors 20%
Polycystic Ovary Syndrome 15%
Endometriosis 10%
Medical Treatments 10%

Top Signs and Symptoms of Low AMH Levels:

Symptom Percentage
Irregular Menstrual Cycles 30%
Shorter Menstrual Cycles 25%
Premature Ovarian Aging 20%
Difficulty Conceiving 15%
Low Antral Follicle Count 10%

Conclusion

This blog provides a detailed understanding of low AMH levels, their impact on fertility, and various treatment options. By adopting a healthy lifestyle and considering medical interventions, women with low AMH can improve their chances of conception.

About The Author
Dr. Richika Sahay

MBBS (Gold Medalist), DNB (Obst & Gyne), MNAMS, MRCOG (London-UK), Fellow IVF, Fellow MAS, Infertility (IVF) Specialist & Gynae Laparoscopic surgeon,[Ex AIIMS & Sir Gangaram Hospital, New Delhi]. Read more

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