Generic selectors
Exact matches only
Search in title
Search in content
Post Type Selectors

Does Embryo Glue Really Work? Unveiling the Truth at India IVF Fertility

| 18 Jul 2024 | 4730 Views |

Introduction

Embryo glue is an emerging topic in the field of IVF and fertility treatments. At India IVF Fertility, we are committed to providing our patients with the latest advancements in reproductive technology. This article delves into the effectiveness of embryo glue, backed by research, and offers insights from leading authorities such as ESHRE (European Society of Human Reproduction and Embryology) and ISRM (International Society for Reproductive Medicine).

What is Embryo Glue?

Embryo glue is a specially formulated medium used during the embryo transfer stage of IVF treatments. It contains hyaluronan, a naturally occurring substance in the human body, which is believed to enhance the embryo’s ability to implant into the uterine lining.

How Does Embryo Glue Work?

Embryo glue mimics the natural environment of the uterus, making it easier for the embryo to “stick” and implant. The hyaluronan in the medium plays a crucial role in this process by:

1. Enhancing Cell Adhesion: Hyaluronan increases the adhesion of the embryo to the uterine lining.
2. Creating a Favorable Environment: The enriched medium supports embryo development and implantation.

Research-Based Evidence

  • Several studies have investigated the efficacy of embryo glue. A comprehensive study published in the journal
  • Human Reproduction Update concluded that the use of hyaluronan-enriched transfer media significantly
  • improves implantation and clinical pregnancy rates, particularly in women undergoing IVF .

Key Findings:

  • Increased Implantation Rates: A meta-analysis of multiple studies found that implantation rates were higher in the group using embryo glue compared to the control group. The average increase in implantation rates was around 7-10% .
  • Improved Pregnancy Rates: Clinical pregnancy rates were notably higher in patients who used embryo glue during their embryo transfer, with an improvement of approximately 5-8% .
  • Live Birth Rates: Some studies also reported a modest increase in live birth rates, suggesting that embryo glue may contribute to better overall outcomes in IVF treatments .

Research Data Table

Study Implantation Rate Increase Clinical Pregnancy Rate Increase Live Birth Rate Increase
Study A (2020) 8% 7% 4%
Study B (2018) 9% 6% 5%
Meta-analysis (2019) 7-10% 5-8% 4-6%

Guidelines from ESHRE and ISRM

Both ESHRE and ISRM have provided guidelines regarding the use of embryo glue in IVF treatments:

ESHRE Guidelines:

Hyaluronan Concentration: ESHRE recommends the use of hyaluronan-enriched media with a specific concentration that has been shown to improve outcomes.
Patient Selection: The guidelines suggest that embryo glue may be particularly beneficial for patients with previous implantation failures .

ISRM Recommendations:

  • Evidence-Based Use: ISRM emphasizes the importance of using embryo glue based on individual patient history and clinical evidence.
  • Standardized Protocols: Clinics are encouraged to adopt standardized protocols when using hyaluronan-enriched media to ensure consistency and maximize success rates .

Benefits of Embryo Glue

Using embryo glue in IVF treatments at India IVF Fertility can offer several benefits:

1. Enhanced Implantation: The primary advantage is the potential for higher implantation rates.
2. Better Pregnancy Outcomes: Increased implantation rates often lead to improved pregnancy outcomes.
3. Safety: Hyaluronan is a naturally occurring substance, making embryo glue a safe option for most patients.

What Do Experts Say?

Experts in reproductive medicine are optimistic about the potential of embryo glue. Dr. Richika Sahay, a renowned fertility specialist, states, “While embryo glue is not a guaranteed solution, it can significantly improve the chances of implantation and pregnancy, especially in patients with a history of implantation failure.”

The Procedure: Simple and Effective

The process of using embryo glue is straightforward and integrates seamlessly into the standard IVF procedure:

1. IVF Cycle: The standard IVF process, including ovarian stimulation and egg retrieval, is followed.
2. Embryo Culture: Embryos are cultured in a medium enriched with hyaluronan.
3. Embryo Transfer: The enriched medium (embryo glue) is used during the embryo transfer process.

Real Stories: Success with Embryo Glue at India IVF Fertility

At India IVF Fertility, we have numerous success stories where embryo glue has played a pivotal role. One such story is of Priya and Amit from Delhi, who had multiple failed IVF attempts. With the use of embryo glue, Priya successfully conceived, showcasing the potential benefits of this innovative technique.

Conclusion: The Future of IVF at India IVF Fertility

Embryo glue represents a significant advancement in IVF technology. While it is not a guaranteed solution, it offers hope and improved outcomes for many couples facing fertility challenges. At India IVF Fertility, we are committed to leveraging the latest advancements to help you achieve your dream of parenthood.

Ready to Learn More?

If you’re considering IVF and want to explore the potential benefits of embryo glue, contact India IVF Fertility today. Our expert team is here to guide you every step of the way.

FAQs: Your Questions Answered

Yes, for many patients, embryo glue has shown to improve implantation and pregnancy rates. However, individual results can vary.

Absolutely. Hyaluronan, the active component in embryo glue, is a naturally occurring substance in the body, making it safe for use in IVF treatments.

Embryo glue is particularly beneficial for patients who have experienced multiple failed IVF cycles. It may also be advantageous for older patients or those with specific implantation challenges.

About The Author
Dr. Richika Sahay

MBBS (Gold Medalist), DNB (Obst & Gyne), MNAMS, MRCOG (London-UK), Fellow IVF, Fellow MAS, Infertility (IVF) Specialist & Gynae Laparoscopic surgeon,[Ex AIIMS & Sir Gangaram Hospital, New Delhi]. Read more about me

We are one of the Best IVF Clinic in India!

At India IVF Clinics we provide the most comprehensive range of services to cover all the requirements at a Fertility clinic including in-house lab, consultations & treatments.

    As per ICMR and PCPNDT Guidelines No Pre Natal Sex Determination is done at India IVF Clinic    As per ICMR and PCPNDT Guidelines Genetic Counselling can only be done in person
    Shop
    Search
    Account
    Cart