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Your Guide to Understanding and Treating Unexplained Infertility Decoding the Unknown

Your Guide to Understanding and Treating Unexplained Infertility: Decoding the Unknown:

| 02 Aug 2023 | 6534 Views |

What is Unexplained Infertility?

The term ‘Unexplained Infertility’ sounds like an oxymoron, doesn’t it? Here’s the deal – unexplained infertility is a situation where a couple is unable to conceive despite having normal reproductive health. In other words, even after numerous tests and evaluations, the cause of infertility remains unknown.

How Common is Unexplained Infertility?

Unexplained infertility isn’t as rare as you might think. According to the American Society for Reproductive Medicine1, approximately 10 to 15% of couples globally are affected by unexplained infertility. In other words, this elusive condition is more common than one might anticipate.

Is Pregnancy Possible with Unexplained Infertility?

The million-dollar question — can you get pregnant with unexplained infertility? The answer is a resounding “yes.” Although the journey may be more challenging, it is by no means impossible.

How to Get Pregnant with Unexplained Infertility?

While unexplained infertility can be a frustrating diagnosis, it doesn’t mean the end of the road. Couples can still pursue various fertility treatments such as medication, Intrauterine Insemination (IUI), In Vitro Fertilization (IVF), and lifestyle modifications.

Causes of Unexplained Infertility:

While the condition is “unexplained” in medical terminology, several potential underlying factors could play a role:

  • Minor endometrial issues
  • Sperm function abnormalities
  • Egg quality deterioration
  • Immune disorders

These factors often escape standard fertility evaluations, contributing to the unexplained part of the diagnosis.

Symptoms of Unexplained Infertility:

The symptoms of unexplained infertility can be, well, unexplained. Often, there are no noticeable symptoms apart from the inability to conceive. Couples usually have normal sexual health and menstrual cycles, making the condition even more challenging to detect.

Diagnosing Unexplained Infertility:

Diagnosis involves a series of fertility evaluations for both partners, including:

  • Semen Analysis
  • Ovulation Testing
  • Hysterosalpingography (HSG)
  • Laparoscopy

When these tests come out normal, and the couple still struggles to conceive, unexplained infertility is often the diagnosis.

Treatment Options for Unexplained Infertility:

Several treatment options are available, including:

  • Fertility drugs: These help stimulate ovulation.
  • Intrauterine Insemination (IUI): This involves placing healthy sperm directly into the uterus.
  • In Vitro Fertilization (IVF): This process involves fertilizing an egg outside the body and then implanting it into the uterus.

Comparison of Unexplained Infertility Treatment Success Rates:

Treatment Option Success Rate
Fertility Drugs 20% per cycle
IUI 10-20% per cycle
IVF 60-80% per cycle

Which is the Best Treatment for Unexplained Infertility?

The “best” treatment varies greatly from one couple to another and depends on a multitude of factors like age, overall health, and personal preferences. That said, IVF often emerges as a promising choice given its relatively high success rate.

Can Unexplained Infertility Be Prevented?

Unexplained infertility is as unpredictable as its name suggests. While you can’t necessarily prevent it, maintaining a healthy lifestyle and seeking regular check-ups can help manage the situation.

Tips for Conceiving with Unexplained Infertility:

  • Eat a balanced diet and exercise regularly.
  • Avoid smoking and limit alcohol intake.
  • Seek support; the journey can be emotionally taxing.


Unexplained infertility is a condition where a couple cannot conceive despite having normal reproductive health.

Around 10 to 15% of couples globally are affected by unexplained infertility.

Yes, it is possible with the right treatment approach.

Minor endometrial issues, sperm function abnormalities, egg quality deterioration, and immune disorders could potentially be involved.

It involves a series of tests like semen analysis, ovulation testing, HSG, and laparoscopy.

Options include fertility drugs, IUI, and IVF.

Fertility drugs have a 20% success rate per cycle, IUI 10-20%, and IVF around 40-45%.

The "best" treatment varies, but IVF often emerges as a promising choice due to its high success rate.

It can't be prevented per se, but maintaining a healthy lifestyle and regular check-ups can help manage it.

Eating a balanced diet, regular exercise, avoiding smoking, limiting alcohol intake, and seeking support are some tips.

About The Author
India IVF Clinic

Best IVF Centre At India IVF Fertility, located in Delhi, Noida, Gurgaon, Gwalior, Srinagar to get best infertility treatment with high success rates.

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